Scientific study confirms the potential anti-cancer blood umbilical Stem cells

Scientific study confirms the potential anti-cancer blood umbilical Stem cells inhibit the proliferation of normal cells tumor of breast cancer in animals


The extracellular matrix (complex network of proteins and polysaccharides secreted by cells) stem cells mesenchymal cells of umbilical cord blood can inhibit the growth of tumor cells in metastatic tumors aggressive, a study published in the journal Cancer Letters .

The study authors show that this result is achieved because the extracellular matrix of mesenchymal stem cells obtained from umbilical cord blood cells induce tumor increased levels of a protein with anti- tumor. Simultaneously, this matrix induces the secretion of a Another factor that suppresses a signaling pathway quite important in tumor formation.

In this investigation, tumor cells of breast cancer were two days exposed during the mesenchymal stem cells from Cord blood and was then injected into female mice. After 43 days, the volumes of tumors in group treated with stem cells were significantly lower than in control animals.




The study shows that the extracellular matrix stem cells umbilical cord blood could inhibit the growth of cancer cells and has the potential to suppress the progression tumor.

Cancer is a complex disease in which there is a relationship dynamics between tumor cells and the microenvironment that involves. In tumors are cancer stem cells that have some characteristics in common with stem cells normal. Both types of stem cells are deeply
influenced by their microenvironments surrounding the that dictates their cell fate and behavior.

Understanding the inhibitory effect of cell microenvironment mesenchymal stem cells may ultimately allow the development of new therapeutic strategies to combat cancer.

David Ferreira, Crioestaminal responsible physician, states that ”This is a work of research that clarifies the relationship between some substances from the extracellular matrix produced by mesenchymal stem cells, with inhibitory potential of tumor growth and may thus help in defining new therapeutic targets in treatment of cancer. “